An Arbitrary-Modal Fusion Network for Volumetric Cranial Nerves Tract Segmentation

The segmentation of cranial nerves (CNs) tract provides a valuable quantitative tool for the analysis of the morphology and trajectory of individual CNs. Multimodal CNs tract segmentation networks, e.g., CNTSeg, which combine structural Magnetic Resonance Imaging (MRI) and diffusion MRI, have achieved promising segmentation performance. However, it is laborious or even infeasible to collect complete multimodal data in clinical practice due to limitations in equipment, user privacy, and working conditions. In this work, we propose a novel arbitrary-modal fusion network for volumetric CNs tract segmentation, called CNTSeg-v2, which trains one model to handle different combinations of available modalities. Instead of directly combining all the modalities, we select T1-weighted (T1w) images as the primary modality due to its simplicity in data acquisition and contribution most to the results, which supervises the information selection of other auxiliary modalities. Our model encompasses an Arbitrary-Modal Collaboration Module (ACM) designed to effectively extract informative features from other auxiliary modalities, guided by the supervision of T1w images. Meanwhile, we construct a Deep Distance-guided Multi-stage (DDM) decoder to correct small errors and discontinuities through signed distance maps to improve segmentation accuracy. We evaluate our CNTSeg-v2 on the Human Connectome Project (HCP) dataset and the clinical Multi-shell Diffusion MRI (MDM) dataset. Extensive experimental results show that our CNTSeg-v2 achieves state-of-the-art segmentation performance, outperforming all competing methods.

A Survey of Interactive Generative Video

Interactive Generative Video (IGV) has emerged as a crucial technology in response to the growing demand for high-quality, interactive video content across various domains. In this paper, we define IGV as a technology that combines generative capabilities to produce diverse high-quality video content with interactive features that enable user engagement through control signals and responsive feedback. We survey the current landscape of IGV applications, focusing on three major domains: 1) gaming, where IGV enables infinite exploration in virtual worlds; 2) embodied AI, where IGV serves as a physics-aware environment synthesizer for training agents in multimodal interaction with dynamically evolving scenes; and 3) autonomous driving, where IGV provides closed-loop simulation capabilities for safety-critical testing and validation. To guide future development, we propose a comprehensive framework that decomposes an ideal IGV system into five essential modules: Generation, Control, Memory, Dynamics, and Intelligence. Furthermore, we systematically analyze the technical challenges and future directions in realizing each component for an ideal IGV system, such as achieving real-time generation, enabling open-domain control, maintaining long-term coherence, simulating accurate physics, and integrating causal reasoning. We believe that this systematic analysis will facilitate future research and development in the field of IGV, ultimately advancing the technology toward more sophisticated and practical applications.

UniBiomed: A Universal Foundation Model for Grounded Biomedical Image Interpretation

Multi-modal interpretation of biomedical images opens up novel opportunities in biomedical image analysis. Conventional AI approaches typically rely on disjointed training, i.e., Large Language Models (LLMs) for clinical text generation and segmentation models for target extraction, which results in inflexible real-world deployment and a failure to leverage holistic biomedical information. To this end, we introduce UniBiomed, the first universal foundation model for grounded biomedical image interpretation. UniBiomed is based on a novel integration of Multi-modal Large Language Model (MLLM) and Segment Anything Model (SAM), which effectively unifies the generation of clinical texts and the segmentation of corresponding biomedical objects for grounded interpretation. In this way, UniBiomed is capable of tackling a wide range of biomedical tasks across ten diverse biomedical imaging modalities. To develop UniBiomed, we curate a large-scale dataset comprising over 27 million triplets of images, annotations, and text descriptions across ten imaging modalities. Extensive validation on 84 internal and external datasets demonstrated that UniBiomed achieves state-of-the-art performance in segmentation, disease recognition, region-aware diagnosis, visual question answering, and report generation. Moreover, unlike previous models that rely on clinical experts to pre-diagnose images and manually craft precise textual or visual prompts, UniBiomed can provide automated and end-to-end grounded interpretation for biomedical image analysis. This represents a novel paradigm shift in clinical workflows, which will significantly improve diagnostic efficiency. In summary, UniBiomed represents a novel breakthrough in biomedical AI, unlocking powerful grounded interpretation capabilities for more accurate and efficient biomedical image analysis.

CoCo-Bench: A Comprehensive Code Benchmark For Multi-task Large Language Model Evaluation

Large language models (LLMs) play a crucial role in software engineering, excelling in tasks like code generation and maintenance. However, existing benchmarks are often narrow in scope, focusing on a specific task and lack a comprehensive evaluation framework that reflects real-world applications. To address these gaps, we introduce CoCo-Bench (Comprehensive Code Benchmark), designed to evaluate LLMs across four critical dimensions: code understanding, code generation, code modification, and code review. These dimensions capture essential developer needs, ensuring a more systematic and representative evaluation. CoCo-Bench includes multiple programming languages and varying task difficulties, with rigorous manual review to ensure data quality and accuracy. Empirical results show that CoCo-Bench aligns with existing benchmarks while uncovering significant variations in model performance, effectively highlighting strengths and weaknesses. By offering a holistic and objective evaluation, CoCo-Bench provides valuable insights to guide future research and technological advancements in code-oriented LLMs, establishing a reliable benchmark for the field.

Low-Rank Adaptive Structural Priors for Generalizable Diabetic Retinopathy Grading

Diabetic retinopathy (DR), a serious ocular complication of diabetes, is one of the primary causes of vision loss among retinal vascular diseases. Deep learning methods have been extensively applied in the grading of diabetic retinopathy (DR). However, their performance declines significantly when applied to data outside the training distribution due to domain shifts. Domain generalization (DG) has emerged as a solution to this challenge. However, most existing DG methods overlook lesion-specific features, resulting in insufficient accuracy. In this paper, we propose a novel approach that enhances existing DG methods by incorporating structural priors, inspired by the observation that DR grading is heavily dependent on vessel and lesion structures. We introduce Low-rank Adaptive Structural Priors (LoASP), a plug-and-play framework designed for seamless integration with existing DG models. LoASP improves generalization by learning adaptive structural representations that are finely tuned to the complexities of DR diagnosis. Extensive experiments on eight diverse datasets validate its effectiveness in both single-source and multi-source domain scenarios. Furthermore, visualizations reveal that the learned structural priors intuitively align with the intricate architecture of the vessels and lesions, providing compelling insights into their interpretability and diagnostic relevance.

Adaptation Method for Misinformation Identification

Multimodal fake news detection plays a crucial role in combating online misinformation. Unfortunately, effective detection methods rely on annotated labels and encounter significant performance degradation when domain shifts exist between training (source) and test (target) data. To address the problems, we propose ADOSE, an Active Domain Adaptation (ADA) framework for multimodal fake news detection which actively annotates a small subset of target samples to improve detection performance. To identify various deceptive patterns in cross-domain settings, we design multiple expert classifiers to learn dependencies across different modalities. These classifiers specifically target the distinct deception patterns exhibited in fake news, where two unimodal classifiers capture knowledge errors within individual modalities while one cross-modal classifier identifies semantic inconsistencies between text and images. To reduce annotation costs from the target domain, we propose a least-disagree uncertainty selector with a diversity calculator for selecting the most informative samples. The selector leverages prediction disagreement before and after perturbations by multiple classifiers as an indicator of uncertain samples, whose deceptive patterns deviate most from source domains. It further incorporates diversity scores derived from multi-view features to ensure the chosen samples achieve maximal coverage of target domain features. The extensive experiments on multiple datasets show that ADOSE outperforms existing ADA methods by 2.72\% $\sim$ 14.02\%, indicating the superiority of our model.

DIDS: Domain Impact-aware Data Sampling for Large Language Model Training

Large language models (LLMs) are commonly trained on multi-domain datasets, where domain sampling strategies significantly impact model performance due to varying domain importance across downstream tasks. Existing approaches for optimizing domain-level sampling strategies struggle with maintaining intra-domain consistency and accurately measuring domain impact. In this paper, we present Domain Impact-aware Data Sampling (DIDS). To ensure intra-domain consistency, a gradient clustering algorithm is proposed to group training data based on their learning effects, where a proxy language model and dimensionality reduction are employed to reduce computational overhead. To accurately measure domain impact, we develop a Fisher Information Matrix (FIM) guided metric that quantifies how domain-specific parameter updates affect the model's output distributions on downstream tasks, with theoretical guarantees. Furthermore, to determine optimal sampling ratios, DIDS combines both the FIM-guided domain impact assessment and loss learning trajectories that indicate domain-specific potential, while accounting for diminishing marginal returns. Extensive experiments demonstrate that DIDS achieves 3.4% higher average performance while maintaining comparable training efficiency.

Transferable Deployment of Semantic Edge Inference Systems via Unsupervised Domain Adaption

This paper investigates deploying semantic edge inference systems for performing a common image clarification task. In particular, each system consists of multiple Internet of Things (IoT) devices that first locally encode the sensing data into semantic features and then transmit them to an edge server for subsequent data fusion and task inference. The inference accuracy is determined by efficient training of the feature encoder/decoder using labeled data samples. Due to the difference in sensing data and communication channel distributions, deploying the system in a new environment may induce high costs in annotating data labels and re-training the encoder/decoder models. To achieve cost-effective transferable system deployment, we propose an efficient Domain Adaptation method for Semantic Edge INference systems (DASEIN) that can maintain high inference accuracy in a new environment without the need for labeled samples. Specifically, DASEIN exploits the task-relevant data correlation between different deployment scenarios by leveraging the techniques of unsupervised domain adaptation and knowledge distillation. It devises an efficient two-step adaptation procedure that sequentially aligns the data distributions and adapts to the channel variations. Numerical results show that, under a substantial change in sensing data distributions, the proposed DASEIN outperforms the best-performing benchmark method by 7.09% and 21.33% in inference accuracy when the new environment has similar or 25 dB lower channel signal to noise power ratios (SNRs), respectively. This verifies the effectiveness of the proposed method in adapting both data and channel distributions in practical transfer deployment applications.

CheatAgent: Attacking LLM-Empowered Recommender Systems via LLM Agent

Recently, Large Language Model (LLM)-empowered recommender systems (RecSys) have brought significant advances in personalized user experience and have attracted considerable attention. Despite the impressive progress, the research question regarding the safety vulnerability of LLM-empowered RecSys still remains largely under-investigated. Given the security and privacy concerns, it is more practical to focus on attacking the black-box RecSys, where attackers can only observe the system's inputs and outputs. However, traditional attack approaches employing reinforcement learning (RL) agents are not effective for attacking LLM-empowered RecSys due to the limited capabilities in processing complex textual inputs, planning, and reasoning. On the other hand, LLMs provide unprecedented opportunities to serve as attack agents to attack RecSys because of their impressive capability in simulating human-like decision-making processes. Therefore, in this paper, we propose a novel attack framework called CheatAgent by harnessing the human-like capabilities of LLMs, where an LLM-based agent is developed to attack LLM-Empowered RecSys. Specifically, our method first identifies the insertion position for maximum impact with minimal input modification. After that, the LLM agent is designed to generate adversarial perturbations to insert at target positions. To further improve the quality of generated perturbations, we utilize the prompt tuning technique to improve attacking strategies via feedback from the victim RecSys iteratively. Extensive experiments across three real-world datasets demonstrate the effectiveness of our proposed attacking method.

Seaweed-7B: Cost-Effective Training of Video Generation Foundation Model

This technical report presents a cost-efficient strategy for training a video generation foundation model. We present a mid-sized research model with approximately 7 billion parameters (7B) called Seaweed-7B trained from scratch using 665,000 H100 GPU hours. Despite being trained with moderate computational resources, Seaweed-7B demonstrates highly competitive performance compared to contemporary video generation models of much larger size. Design choices are especially crucial in a resource-constrained setting. This technical report highlights the key design decisions that enhance the performance of the medium-sized diffusion model. Empirically, we make two observations: (1) Seaweed-7B achieves performance comparable to, or even surpasses, larger models trained on substantially greater GPU resources, and (2) our model, which exhibits strong generalization ability, can be effectively adapted across a wide range of downstream applications either by lightweight fine-tuning or continue training. See the project page at https://seaweed.video/